Product details
apple extract phloretin cas60-82-2 whitening agents control oily
Product introduction of the Phloretin
Phloretin is a dihydrochalcone compound, is a new natural skin whitening agent, mainly distributed in apples and other juicy fruit peel and root bark. Phloretin has a weak estrogen activity.
Product parameter of the Phloretin
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Trade Name: Shaanxi Huatai Bio-fine Chemical Co., Ltd. |
Common Name: Phloretin |
Chemical Name : 2',4',6'-TRIHYDROXY-3-(4-HYDROXYPHENYL)PROPIOPHENONE |
CAS No.: 60-82-2 |
EINECS No.: 200-488-7 |
Molecular Formula: C15H14O5 |
Molecular Structure: |
Characteristics: White powder |
Solubility: Dissolved in ethanol, 1,3-butanediol. Do not dissolved in water |
Specification: Cosmetic grade |
Category: Skin Care |
Features: The Studies have shown that phloretin can inhibiting melanocytes, inhibiting tyrosinase activity, and has effects on various skin pigmentation. Phloretin also has Anti-inflammatory and immunosuppressive effects. Research showed that cause the phloretin, NO release volume of macrophage was significantly decreased under the stimulation of lipopolysaccharide (LPS) and IFN-γ. |
Typical Dosage: 3‰-5‰ |
Packing: 1kg aluminum foil bag |
Transport: Non-hazardous cargo(IMO/IATA) |
Remarks: Safety and efficacy report available upon request. |
Product feature application of the Phloretin
Anti-inflammatory and immunosuppressive effects. Research showed that cause the phloretin, NO release volume of macrophage was significantly decreased under the stimulation of lipopolysaccharide (LPS) and IFN-γ. Phloretin has a potential anti-inflammatory effect. In immunosuppression, studies have shown that phloretin has a significant inhibitory effect on mouse T lymphocyte activation.
Phloretin induced cytotoxicity on lymphocytes N=6, *±S.control
Group |
Dose/μmol·L-1 |
A |
Survival rate/% |
Negative |
|||
Control |
0.140±0.002 |
/ |
|
Positive |
|||
Control |
0.365±0.007 |
100 |
|
Phloretin |
40 |
0.332±0.013 |
88.87 |
60 |
0.316±0.021 |
81.48 |
|
80 |
0.297±0.015 |
72.68 |
Figure :Proliferation of lymphocytes analyzed by CFSE-labelling (n = 4, x ± s).
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Product qualification of the Phloretin
Deliver, shipping and serving of the Phloretin Applications: Widely used in cosmetic product as cream, paste, water solution and emulsion.
1. 1kg with double plastic container inside/Aluminum foil bag outside. |
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